Visibility Vol 16 Issue 3, 2022

Development of New Treatment for Age related Macular Degeneration- TSPO Ligand CB204

Age related Macular degeneration has been to be characterized by cholesterol dysfunction and dysregulation. The 18 KDa translocator protein (TSPO) is a mitochondrial outer membrane protein responsible for transporting cholesterol from the mitochondrial outer membrane to the inner membrane. TSPO is highly expressed in retinal pigment epithelial (RPE) cells, and TSPO ligands have shown therapeutic potential for the treatment of AMD. Here, we characterize a new ligand which has not been studied on the ARPE-19 cell line; CB204.

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Well-Being and Mental Health Factors among Informal Caregivers of Individuals with Visual Impairments

Callie Victor, PhD, OTR/L, CLA; Matthew Haase, MS, OTR/L, ATC; Michael Bown; Lindsey Bates, OTR; Michael Centra, OTR/L; Jaclyn Sachleben; Elizabeth Tyson; Michelle Gamber, DrPH; Suleiman Alibhai

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Stand Magnifier Optical Strategies

Gregg Baldwin, OD

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Characteristics of Older Bioptic Drivers: Effects of Increasing Age on Driving Safety

Bradley E. Dougherty, OD, PhD

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